1ohh.. .im sorry..... i didn read question carefully... i thought ....we hv to maximise conc of products...
y i crossed aldol condensation v prefer ,1 aldehyde with no alpha hydrogen and other aldehyde or keto with alpha hydrogen der's a possibility for formation of 2 pdts.how can u minimise d possibility of 1 pdt out of d 2.
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5 Answers
1in ur case, as the aldehyde has no alpha hydrogen, the only to pdts possible cud be
1)ketone attacking the aldehyde,
2)ketone attacking itself.
here, in the second case if the ketone is stearically hindered, then the possibility of a self aldol reaxn. is automatically reduced.
how to minimise the 2nd pdt, hmmm, proly by altering the concentrations, increasing the conc. of the aldehyde wid no alpha hyd., and relatively maintaining an optimum conc of the ketone...
sumone try dis out..its a q. worth attempting..
cheers!!
1well....its true.tht attack on aldehye is much easier thn attack on ketone.....by a ketone.....
so we easily get....the 1 product...(attack of ketone on aldhyde)
to maximise other product we can gradually add aldehyde(wid no alpha h) in soln....already containing ketone and base....
1PARNIKA actually wat gordo said is right.wen v use max of aldehyde and bit of ionized keto wid alpha hydrogen then v can get 1 pdt as d keto can't look for an opportunity to attack itself.
@gordo----awsome reply ,thnx 4 praising d question.do correct me if i m wrong.
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