isoelectric point of amino acid

what is the iso electric point of lysine?

It is given that

pKa1 = 2.18

pKa2 = 8.95

pKa3=10.53

1 Answers

1
rahul wadhwani ·

hey plz specify abt Ka1,ka2,ka3 i.e which is of acid & base-1,base-2 plz but i m providing formula & process
pI=pKa2+pKa3/2
where Ka2 dissociation constant of cation before Zwitter ion &
Ka3 dissociation constant of zwitter ion itself to give anion

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