1
~AjInKyA~
·2008-11-07 10:44:45
i know tat Methyl Lithium is SUPER base
Not all nucleophiles are strong enough to act as bases and not all bases make good nucleophiles.
li has jus 1 e- so it can donate easily
but here grignard forms substitution most probably
and methyl lithium not
si my gues is >>>>>>>>>>better nucleophile : Methyl Lithium
corect me if m rong
>>>>>>>>>>
1
voldy
·2008-11-08 19:06:29
I agree with Abhishek , why does everybody write CORRECT ME IF I'M WRONG?
coming to your Q , weaker baese make better nucleophiles.
both are equally good , except that METHYL LITHIUM IS costly , and thus Grignard reagent is more commonly used.
for yield both are very similsr doesn't make much of a difference